PHYTOBIOACTIVE ExpoZen®
PHYTOBIOACTIVE, quintessence of Nature, maximum concentration of natural active ingredients
ACTION
Anti-exposome
Sensitive & reactive skin microbiota modulator
GREENTECH INNOVATION
Systemic approach of the sensitive skin care
(skin & microbiota)
Characterization of the poorly known sensitive skin microbiota & its modulation
Anti-Exposome effect
DESCRIPTION
Concentrated extract of the tropical red seaweed Halymenia durvillei sourced in the Indian Ocean, titrated in sulphated oligosaccharides obtained by radical depolymerisation.
DESCRIPTION
EXPOZEN® is a COSMOS-approved natural active ingredient, titrated in sulphated oligosaccharides from Halymenia durvillei (tropical red seaweed from the Indian Ocean), to intensively soothe sensitive & reactive skin stressed by the exposome and to rebalance the skin microbiota to restore a healthy comfortable skin.
MECHANISM
EXPOZEN® was desgined by GREENTECH R&D according to a systemic approach, by targeting both skin and microbiota which are interconnected.
At skin level, on skin explants, EXPOZEN® limits mediators of inflammation and neuroinflammation responses involved in skin sensitivity. It particularly decreases the expression of NK1-R (substance P receptor) and TRPV1 (major receptor involved in heat and pain sensation, in nociception), both of which are major mediators of neurogenic inflammation and itch. On reconstructed epidermis, EXPOZEN® strengthens the skin’s resistance by increasing the thickness of the epidermis. It also contributes to limit premature skin aging by modulating telomerase activity and mTor activation.
At microbiota level, a metagenomic analysis on skin surface samples collected during the clinical study allowed GREENTECH scientists to characterize the poorly known microbiota of sensitive skin and to demonstrate beneficial effects of EXPOZEN®: it maintains the diversity of skin microbiota, reduces the bacteria Corynebacterium kroppenstedtii involved in inflammation and redness while promoting Staphylococcus epidermidis, a commensal bacteria known to contribute to skin health.
COSMETIC BENEFITS
EXPOZEN® reduces skin sensitivity and reactivity which can affect up to 50% of the population. EXPOZEN® offers a soothing effect to 90% of volunteers in only 5min after the first use. After 28 days, it significantly reduces the major signs of skin sensitivity (irritability, heat sensation, pain, flushes and redness) according to the Sensitive Scale SS-10 developed by Pr Misery et al. (2014). It also reduces installed facial redness (erythrosis) as proved by innovative videocapilloscopy method.
APPLICATION
• Sensitive and reactive skin products
• Intensive soothing care
• Anti-redness cosmetics
• Skin barrier repair cosmetics
• Well-aging for sensitive skin
• Skin microbiota regulator
